Ghabbour, Hazem A.

Top Publications

Top Publications Authored or Co-Authored by "Ghabbour, Hazem A."

• Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies

  European Journal of Medicinal Chemistry, Volume 139, Year 2017, Citations 106
• Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII

  European Journal of Medicinal Chemistry, Volume 110, Year 2016, Citations 71
• Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1-substituted-4-(4-methoxybenzyl)phthalazine derivatives

  European Journal of Medicinal Chemistry, Volume 113, Year 2016, Citations 69
• Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells as apoptosis-inducing agents

  Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 32, No. 1, Year 2017, Citations 66
• Fluorescence spectroscopic and molecular docking studies of the binding interaction between the new anaplastic lymphoma kinase inhibitor crizotinib and bovine serum albumin

  Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, Volume 171, Year 2017, Citations 63