Laleu, Benoît

Top Publications

Top Publications Authored or Co-Authored by "Laleu, Benoît"

• Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

  PLoS Pathogens, Volume 12, No. 7, Article e1005763, Year 2016, Citations 346
• Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

  Journal of Medicinal Chemistry, Volume 64, No. 9, Year 2021, Citations 44
• The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

  Cell Chemical Biology, Volume 29, No. 5, Year 2022, Citations 33
• Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2

  ChemMedChem, Volume 17, No. 22, Article e202200393, Year 2022, Citations 20
• Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out

  SLAS Discovery, Volume 27, No. 6, Year 2022, Citations 16