Lambert, Gilles

Top Publications

Top Publications Authored or Co-Authored by "Lambert, Gilles"

• PCSK9 Modulates the Secretion But Not the Cellular Uptake of Lipoprotein(a) Ex Vivo: An Effect Blunted by Alirocumab

  JACC: Basic to Translational Science, Volume 1, No. 6, Year 2016, Citations 106
• Characterization of Autosomal Dominant Hypercholesterolemia Caused by PCSK9 Gain of Function Mutations and Its Specific Treatment with Alirocumab, a PCSK9 Monoclonal Antibody

  Circulation: Cardiovascular Genetics, Volume 8, No. 6, Year 2015, Citations 92
• Identification and characterization of two non-secreted PCSK9 mutants associated with familial hypercholesterolemia in cohorts from New Zealand and South Africa

  Atherosclerosis, Volume 196, No. 2, Year 2008, Citations 82
• Homozygous familial hypercholesterolemia patients with identical mutations variably express the LDLR (low-density lipoprotein receptor): Implications for the efficacy of evolocumab

  Arteriosclerosis, Thrombosis, and Vascular Biology, Volume 38, No. 3, Year 2018, Citations 64
• Elevated plasma PCSK9 level is equally detrimental for patients with nonfamilial hypercholesterolemia and heterozygous familial hypercholesterolemia, irrespective of low-density lipoprotein receptor defects

  Journal of the American College of Cardiology, Volume 63, No. 22, Year 2014, Citations 62