Brennan, Paul E.

Top Publications

Top Publications Authored or Co-Authored by "Brennan, Paul E."

• A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain

  Chemical Science, Volume 7, No. 3, Year 2016, Citations 81
• 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

  Journal of Medicinal Chemistry, Volume 59, No. 4, Year 2016, Citations 78
• Target 2035-update on the quest for a probe for every protein

  RSC Medicinal Chemistry, Volume 13, No. 1, Year 2022, Citations 63
• The structural basis of fatty acid elongation by the ELOVL elongases

  Nature Structural and Molecular Biology, Volume 28, No. 6, Year 2021, Citations 45
• Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening

  Journal of the American Chemical Society, Volume 141, No. 22, Year 2019, Citations 34