Kuepfer, Lars

Top Publications

Top Publications Authored or Co-Authored by "Kuepfer, Lars"

• A systematic evaluation of the use of physiologically based pharmacokinetic modeling for cross-species extrapolation

  Journal of Pharmaceutical Sciences, Volume 104, No. 1, Year 2015, Citations 92
• Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases

  Journal of Hepatology, Volume 64, No. 4, Year 2016, Citations 90
• Enabling multiscale modeling in systems medicine

  Genome Medicine, Volume 6, No. 3, Article 21, Year 2014, Citations 83
• Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

  Hepatology, Volume 69, No. 2, Year 2019, Citations 81
• Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

  Archives of Toxicology, Volume 93, No. 6, Year 2019, Citations 79