Effects of the Anti-obesity Drugs Vita Slim and Green Tea on Certain Biochemical and Physiological Indices of Obese Adult Male Albino Rats

Background: Because obesity is linked to an increased risk of diabetes and heart disease, the ideal anti-obesity medication would have weight loss that was long-lasting and had few side effects. Objective: To detect if the weight-loss drugs; green tea and Vita slim negatively affect several biochemical and physiological markers. Materials and Methods: Three groups consisted of 21 mature obese male albino rats (with a body weight of 220 ±20 gram): In Group one: control (vehicle treatment), in group two: for a period of 30 days, rats were given Vita slim (0.1mg/kg/day), and in group three: for 30 days, rats were given green tea (0.1 mg/kg/day). Results: Significant changes were observed in the weight of the treated groups, in serum levels of AST/ALT, albumin, triglycerides, low-density lipoproteins (LDL), LDL/HDL ratio, urea, creatinine, as well as triiodothyronine (T3) as compared with the control group. Conclusion: Several physiological and biochemical markers, including kidney and liver functions, have been shown to be negatively impacted by Vita slim and green tea after 30 days of ingestion.