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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Trends in long-term cardiovascular mortality and morbidity in men and women with heart failure of ischemic versus non-ischemic aetiology in Western Australia between 1990 and 2005
International Journal of Cardiology, Volume 158, No. 3, Year 2012
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Description
Background: It is uncertain if improvements in long-term cardiovascular (CV) mortality have occurred in both men and women with ischemic and non-ischemic forms of heart failure (HF). Methods: The Western Australia Hospital Morbidity Database was used to identify all index (first-ever) hospitalizations for HF between 1990 and 2005. Patients were followed until death attributed to cardiovascular causes or censored on December 31, 2006 to determine 5-year survival. Cox proportional hazards models were used to compare the adjusted mortality hazard ratio (HR) during the study follow-up (4-year periods). Results: A total of 21,507 patients (mean age 73.9 years, 49.1% women) were identified. Women were significantly older than men, and less likely to have ischemic HF (38.8% versus 46.1%). Over the period, age-standardized incidence of first HF hospitalization declined but with the least decline in women with non-ischemic HF (- 13.3%) compared to other subgroups. Risk-adjusted 5-year CV mortality declined over the study period, with HR 0.64 (95% CI 0.60-0.68) for patients admitted in 1998-2001 compared to 1990-1993, with significant improvement in both forms of HF, and in both sexes and across age groups. However, overall total HF hospitalizations increased (+ 26.7%) over the period, particularly for non-ischemic HF (+ 43.7%), of which elderly women formed the predominant group. Conclusions: Risk-adjusted long-term survival improved similarly in men and women, including the elderly, with ischemic and non-ischemic forms of HF during 1990-2005 in Western Australia. However, there was a growing burden of HF hospitalizations particularly for HF of non-ischemic aetiology. © 2011 Elsevier Ireland Ltd.
Authors & Co-Authors
Teng, Tiew-Hwa Katherine
Australia, Perth
The University of Western Australia
Hung, Joseph C.
Australia, Perth
The University of Western Australia
Knuiman, Matthew William
Australia, Perth
The University of Western Australia
Stewart, Simon D.
Australia, Melbourne
Baker Heart and Diabetes Institute
Jacobs, Ian G.
Australia, Perth
The University of Western Australia
Hobbs, Michael S.T.
Australia, Perth
The University of Western Australia
Finn, Judith C.
Australia, Perth
The University of Western Australia
Statistics
Citations: 29
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1016/j.ijcard.2011.01.061
ISSN:
18741754
Research Areas
Environmental
Health System And Policy
Noncommunicable Diseases
Study Design
Cohort Study
Participants Gender
Male
Female