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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Epidemiology of acute kidney injury in surgical intensive care at University Hospital in Egypt. A prospective observational study
Egyptian Journal of Anaesthesia, Volume 29, No. 4, Year 2013
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Description
Introduction The acute kidney injury (AKI) incidence in ICU patients varies widely from 3% to 30%, with mortality ranging from 36% to 90%, depending on the type of ICU, study population, the period during which the study is conducted, and the criteria used to define AKI. There have been many studies about the epidemiology and risk factors of AKI in critically ill patients in the different regions of the world. However, little data on the epidemiology of AKI in critically ill patients are available in Egypt. Objectives The aim of this study was to assess the incidence of AKI among critical ill patients using RIFEL [risk (R), injury (I), failure (F), loss (L), and end-stage kidney disease (E)] classification and to determine the risk factors and outcome of patients who developed AKI in our surgical ICU. Methods We conducted a 6-month prospective observational study in the surgical ICU. Patients were classified daily using the RIFLE criteria. Patients were considered as having new AKI if they did not have AKI on ICU admission and subsequently reached at least class risk during their follow-up. Deterioration of AKI was diagnosed if the patient had increased in RIFLE class compared to the initial classification. Results One hundred and twelve patients were studied. AKI occurred in 40 (35.7%) of patients. The most common risk factors for AKI are APACHE II score (acute physiology and chronic health evaluation score, version II.) and sepsis. APACHEII was lower in non-AKI group than AKI group (17.3 ± 7.5 versus 22.4 ± 7.4, p = 0.001), and sepsis was more common in AKI patients than non-AKI patients (77.5% versus 49% p = 0.004). Patients with AKI had a mortality rate of 67.5% which was more in patients with failure compared with risk patients. APACHEII, AKI, and needs for mechanical ventilation were independent risks for mortality. © 2013 Production and hosting by Elsevier B.V. on behalf of Egyptian Society of Anesthesiologists.
Authors & Co-Authors
Mohamed, Hossam
Egypt, Cairo
Faculty of Medicine
Mukhtar, Ahmed M.
Egypt, Cairo
Faculty of Medicine
Mostafa, Shereen
Egypt, Cairo
Faculty of Medicine
Wageh, Sama
Egypt, Cairo
Faculty of Medicine
Eladawy, Akram A.
Egypt, Cairo
Faculty of Medicine
Zaghlol, Ahmed
Egypt, Cairo
Faculty of Medicine
Hasanin, Ahmed Mohamed
Egypt, Cairo
Faculty of Medicine
Hosni, Mostafa
Egypt, Cairo
Faculty of Medicine
Farrag, Mohamed
Egypt, Cairo
Faculty of Medicine
Botros, Michel
Egypt, Cairo
Faculty of Medicine
Farok, Sara
Egypt, Cairo
Faculty of Medicine
Lotfi, Ahmed
Egypt, Cairo
Faculty of Medicine
Statistics
Citations: 12
Authors: 12
Affiliations: 1
Identifiers
Doi:
10.1016/j.egja.2013.03.003
ISSN:
11101849
e-ISSN:
16871804
Research Areas
Health System And Policy
Noncommunicable Diseases
Violence And Injury
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Egypt