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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Antibody prevalence against haemorrhagic fever viruses in randomized representative central African populations
Research in Virology, Volume 140, No. C, Year 1989
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Description
Between 1985 and 1987, 5,070 randomly selected persons living in 6 central African countries (Cameroon, Central African Republic, Chad, Congo, Equatorial Guinea and Gabon) were checked for serological evidence of haemorrhagic fever. Rural and urban areas were studied, including ecoclimatic zones ranging from dry savana to tropical rain forest. Virus-reactive antibodies were found with all antigens tested, and the global prevalence of positive sera was distributed as follows: Crimean-Congo haemorrhagic fever virus, 0.22%; Rift Valley fever virus, 0.18%; Ebola virus, 12.40%; Marburg virus, 0.39%; Lassa virus, 0.06%; and Hantaan virus, 6.15%. A significant variation in antibody prevalence was observed within the study regions. Association between the viruses was not observed. © 1989 Elsevier.
Authors & Co-Authors
Gonzalez, J. P.
Central African Republic
Institut Français de Recherche Scientifique Pour le Développement en Coopération
Central African Republic, Bangui
Institut Pasteur de Bangui
Josse, Richard L.
Cameroon, Yaounde
Organisation de Coordination Pour la Lutte Contre Les Endémies en Afrique Centrale Cameroon
Johnson, Eugene D.
United States, Fort Detrick
U.s. Army Medical Research Institute of Infectious Diseases
Merlin, Marcel
Cameroon, Yaounde
Organisation de Coordination Pour la Lutte Contre Les Endémies en Afrique Centrale Cameroon
Georges, Alain Jean
Central African Republic, Bangui
Institut Pasteur de Bangui
Abandja, JU
Gabon
Ministère de la Santé
Danyod, M.
Unknown Affiliation
Delaporte, Éric
Cameroon
Centre International de Recherche Médicale de Franceville
Dupont, Alain
Cameroon
Centre International de Recherche Médicale de Franceville
Ghogomu, A.
Cameroon, Yaounde
Agence de Médecine Préventive
Kouka-Bemba, D.
Cameroon, Yaounde
Organisation de Coordination Pour la Lutte Contre Les Endémies en Afrique Centrale Cameroon
Madelon, M. C.
Central African Republic, Bangui
Institut Pasteur de Bangui
Sima, A.
Equatorial Guinea
Ministère de la Santé Publique
Meunier, D. M.Y.
Central African Republic, Bangui
Institut Pasteur de Bangui
Statistics
Citations: 98
Authors: 14
Affiliations: 8
Identifiers
Doi:
10.1016/S0923-2516(89)80112-8
ISSN:
09232516
Research Areas
Infectious Diseases
Study Design
Cross Sectional Study
Study Locations
Cameroon
Central African Republic
Chad
Congo
Equatorial Guinea
Gabon
Guinea