Publication Details

AFRICAN RESEARCH NEXUS

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biochemistry, genetics and molecular biology

Chiral derivatization reagents for drug enantioseparation by high-performance liquid chromatography based upon pre-column derivatization and formation of diastereomers: Enantioselectivity and related structure

Biomedical Chromatography, Volume 15, No. 2, Year 2001

Structures and related enantioselectivities of the respective chiral derivatization reagents (CDRs) for drug enantioseparation by high-performance chromatography based upon pre-column derivatization and diastereomeric formation are reviewed. The elution order of diastereomers caused reaction of some CDRs with enantiomeric amino acids and carboxylic acids. The development of new CDRs available for indirect HPLC methods is also discussed. Copyright © 2001 John Wiley & Sons, Ltd.

Statistics
Citations: 49
Authors: 3
Affiliations: 4
Identifiers
Doi: 10.1002/bmc.41
ISSN: 02693879

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