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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Management of patients with multidrugresistant/ extensively drug-resistant tuberculosis in Europe: A TBNET consensus statement
European Respiratory Journal, Volume 44, No. 1, Year 2014
Notification
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Description
The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) substantially challenges TB control, especially in the European Region of the World Health Organization, where the highest prevalence of MDR/XDR cases is reported. The current management of patients with MDR/XDR-TB is extremely complex for medical, social and public health systems. The treatment with currently available anti-TB therapies to achieve relapse-free cure is long and undermined by a high frequency of adverse drug events, suboptimal treatment adherence, high costs and low treatment success rates. Availability of optimal management for patients with MDR/XDR-TB is limited even in the European Region. In the absence of a preventive vaccine, more effective diagnostic tools and novel therapeutic interventions the control of MDR/XDR-TB will be extremely difficult. Despite recent scientific advances in MDR/XDR-TB care, decisions for the management of patients with MDR/XDR-TB and their contacts often rely on expert opinions, rather than on clinical evidence. This document summarises the current knowledge on the prevention, diagnosis and treatment of adults and children with MDR/XDR-TB and their contacts, and provides expert consensus recommendations on questions where scientific evidence is still lacking. © ERS 2014.
Authors & Co-Authors
Lange, Christoph G.
Germany, Borstel
Research Center Borstel
Abubakar, Ibrahim I.
Germany, Borstel
Research Center Borstel
Alffenaar, Jan Willem C.
Germany, Borstel
Research Center Borstel
Bothamley, Graham Henry
Germany, Borstel
Research Center Borstel
Caminero Luna, José A.
Germany, Borstel
Research Center Borstel
Carvalho, Anna Cristina Calcada
Germany, Borstel
Research Center Borstel
Codecasa, Luigi Ruffo
Germany, Borstel
Research Center Borstel
Crudu, Valeriu
Germany, Borstel
Research Center Borstel
Davies, Peter D.O.
Germany, Borstel
Research Center Borstel
Dedicoat, Martin John
Germany, Borstel
Research Center Borstel
Drobniewski, Francis A.
Germany, Borstel
Research Center Borstel
Duarte, R. A.B.
Germany, Borstel
Research Center Borstel
Erkens, Connie G.M.
Germany, Borstel
Research Center Borstel
Goletti, Delia
Germany, Borstel
Research Center Borstel
Günther, Gunar
Germany, Borstel
Research Center Borstel
Ibraim, Elmira
Germany, Borstel
Research Center Borstel
Kampmann, Beate B.
Germany, Borstel
Research Center Borstel
Kukša, Liga
Germany, Borstel
Research Center Borstel
de Lange, Wiel C.M.
Germany, Borstel
Research Center Borstel
van Leth, Frank C.M.
Germany, Borstel
Research Center Borstel
van Lunzen, Jan
Germany, Borstel
Research Center Borstel
Matteelli, A.
Germany, Borstel
Research Center Borstel
Richard (Dick), Menzies
Germany, Borstel
Research Center Borstel
Monedero-Recuero, Ignacio
Germany, Borstel
Research Center Borstel
Richter, Elvira
Germany, Borstel
Research Center Borstel
Rüsch-Gerdes, Sabine
Germany, Borstel
Research Center Borstel
Sandgren, Andreas
Germany, Borstel
Research Center Borstel
Scardigli, Anna
Germany, Borstel
Research Center Borstel
Skrahina, Alena M.
Germany, Borstel
Research Center Borstel
Tortoli, Enrico
Germany, Borstel
Research Center Borstel
Volchenkov, Grigory V.
Germany, Borstel
Research Center Borstel
Wagner, Dirk
Germany, Borstel
Research Center Borstel
van der Werf, Marieke Johanna
Germany, Borstel
Research Center Borstel
Williams, Bhanu
Germany, Borstel
Research Center Borstel
Yew, Wing W.
Germany, Borstel
Research Center Borstel
Zellweger, Jean Pierre
Germany, Borstel
Research Center Borstel
Cirillo, D. M.
Germany, Borstel
Research Center Borstel
Statistics
Citations: 289
Authors: 37
Affiliations: 1
Identifiers
Doi:
10.1183/09031936.00188313
ISSN:
09031936
Research Areas
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study