Publication Details

AFRICAN RESEARCH NEXUS

SHINING A SPOTLIGHT ON AFRICAN RESEARCH

chemical engineering

Enaminones: Versatile intermediates for natural product synthesis

Pure and Applied Chemistry, Volume 71, No. 6, Year 1999

Efforts in our laboratories to devise a general approach to the synthesis of alkaloids focus on the versatile reactivity of enaminones and related compounds containing the structural unit N-C=C-Z (Z = COR, CO2R, CN, NO2, SO2Ar, etc.). This lecture presents an overview of our research with these useful building blocks. Themes to be elaborated include chemoselectivity and diastereoselectivity in reactions of enaminones, and the challenge of controlling absolute stereochemistry. © 1999 IUPAC.
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