Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Hydroperoxy-cycloartane triterpenoids from the leaves of Markhamia lutea, a plant ingested by wild chimpanzees
Phytochemistry, Volume 70, No. 10, Year 2009
Notification
URL copied to clipboard!
Description
In the framework of the phytochemical investigation of plant species eaten by wild chimpanzees in their natural environment in Uganda, leaf samples of Markhamia lutea were selected and collected. The crude ethyl acetate extract of M. lutea leaves exhibited significant in vitro anti-parasitic activity and low cytotoxicity against MRC5 and KB cells. Fractionation of this extract led to six cycloartane triterpenoids, musambins A-C and their 3-O-xyloside derivatives musambiosides A-C. The structures were elucidated on the basis of spectral studies including mass spectroscopy and extensive 2D NMR. Most of the compounds exhibited mild anti-leishmanial and anti-trypanosomal activities. © 2009 Elsevier Ltd. All rights reserved.
Authors & Co-Authors
Lacroix, Damien
France, Paris
Museum National D'histoire Naturelle
Prado, Soizic
France, Paris
Museum National D'histoire Naturelle
Deville, Alexandre
France, Paris
Museum National D'histoire Naturelle
Krief, Sabrina
France, Paris
Museum National D'histoire Naturelle
Dumontet, Vincent
France, Paris
Cnrs Centre National de la Recherche Scientifique
Kasenene, John Massan K.
Uganda, Kampala
Makerere University
Mouray, Elisabeth
France, Paris
Museum National D'histoire Naturelle
Bories, Christian
France, Paris
Cnrs Centre National de la Recherche Scientifique
Bodo, Bernard
France, Paris
Museum National D'histoire Naturelle
Statistics
Citations: 38
Authors: 9
Affiliations: 3
Identifiers
Doi:
10.1016/j.phytochem.2009.06.020
ISSN:
00319422
Study Locations
Uganda