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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
dentistry
Comparative evaluation of adjunctive oral irrigation in diabetics
Journal of Clinical Periodontology, Volume 29, No. 4, Year 2002
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Description
Aim: The purpose of this study was to assess the response of diabetics to scaling and root planing treatment and subgingival oral irrigation as adjunctive therapy. Method: A total of 52 type 1 and 2 diabetics (mean age 51.3±14) with adult periodontitis were randomized to two groups. Treatment included ultrasonic scaling and scaling and root planing in both groups (control and test) plus subgingival water irrigation 2X daily for the test group. Assessments were made prior to and at 6 and 12 weeks after treatment. Parameters measured were modified gingival index (MGI), probing pocket depth (PPD), plaque index (PI), clinical attachment level (CAL), and bleeding on probing (BOP). Systemic measurement of Reactive Oxygen Species (ROS) generation, cytokines (TNF-α, IL-1β, IL-10, and PGE2), and glycated hemoglobin (HbA 1C). Results: After treatment, analysis of data showed that both groups had clinical and systemic improvement. The test group had a statistically significant reduction for MGI, PI, and BOP compared to controls (p<0.03) at 12 weeks and for ROS generation at 12 weeks (p<0.012). Unlike controls, systemic analysis of cytokines showed a statistically significant reduction from baseline for IL-1β at 6 weeks and PGE2 at 6 and 12 weeks (p<0.05) within test group. Conclusion: These results suggest that scaling and root planing and adjunctive therapy may be of value in establishing a healthy periodontium in diabetics. © Blackwell Munksgaard, 2002.
Authors & Co-Authors
al-Mubarak, Sultan A.
Saudi Arabia, Riyadh
Riyadh Military Hospital
Ciancio, Sebastian G.
United States, Buffalo
University at Buffalo, the State University of new York
Aljada, Ahmad S.
United States, Buffalo
Kaleida Health
Mohanty, P.
United States, Buffalo
Kaleida Health
Mohanty, P.
United States, Buffalo
Kaleida Health
Ross, Candy
United States, Fort Collins
Waterpik Technologies
Dandòna, Paresh
United States, Buffalo
Kaleida Health
Statistics
Citations: 111
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.1034/j.1600-051X.2002.290404.x
ISSN:
03036979
Research Areas
Environmental
Health System And Policy