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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Thrombosis, Recurrent Fetal Loss, and Thrombocytopenia: Predictive Value of the Anticardiolipin Antibody Test
Archives of Internal Medicine, Volume 146, No. 11, Year 1986
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Description
• To determine the predictive value of the IgG anticardiolipin antibody (ACA) test for thrombosis, recurrent fetal loss, and thrombocytopenia, the clinical features of 121 patients with varying antibody levels were studied. When patients were grouped into high-positive, low-positive, and normal groups according to their ACA levels, there were strong statistical correlations with arterial thrombosis, venous thrombosis, fetal loss, thrombocytopenia, and a positive Coombs’ test. At levels of 7 SD and above, the test was highly specific (>80%) and predictive (>70%) for thrombosis, thrombocytopenia, and recurrent fetal loss. This study suggests that the IgG ACA test may be a useful predictor for thrombosis, recurrent fetal loss, and thrombocytopenia in patients with autoimmune disorders. © 1986, American Medical Association. All rights reserved.
Authors & Co-Authors
Asherson, Ronald A.
United Kingdom, London
University College London
Aber, Victor R.
United Kingdom, London
University College London
Hughes, Graham R.V.
United Kingdom, London
University College London
Statistics
Citations: 514
Authors: 3
Affiliations: 1
Identifiers
Doi:
10.1001/archinte.1986.00360230069012
ISSN:
00039926