Publication Details

AFRICAN RESEARCH NEXUS

SHINING A SPOTLIGHT ON AFRICAN RESEARCH

Mapping the drivers of within-host pathogen evolution using massive data sets

Nature Communications, Volume 10, No. 1, Article 3017, Year 2019

Various host factors may impact within-host pathogen evolution. Here, the authors develop a Bayesian approach for identifying host-pathogen interactions using large data sets of pathogen diversity, and apply it to investigate HLA-induced selection in the HIV-1 genome.

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Citations: 13
Authors: 13
Affiliations: 14
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Research Areas
Infectious Diseases