Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Intracranial meningioma in children: Different from adult forms? A series of 21 cases
Neurochirurgie, Volume 56, No. 4, Year 2010
Notification
URL copied to clipboard!
Description
Objective: Intracranial meningiomas are very rare in children, comprising only 0.4 to 4.1% of pediatric tumors and only 1.5 to 1.8% to all intracranial meningiomas. The goal of this study of pediatric meningiomas was to establish their epidemiological profile as well as their clinical and radiological features, to assess the long-term outcome, and compare this result with adult meningioma. Patient and methods: We conducted a retrospective study from June 1983 to June 2007; during this period 521 patients underwent surgery for primary meningioma at the Rabat Hospital, Department of Neurosurgery. Twenty-one patients were under 16 years of age (4%). The clinical charts and imaging data were reviewed. Results: The mean age was 10.3 years (range: 2 to 16 years), with 13 boys and eight girls. In one patient a neurofibromatosis was associated. The mean delay to diagnosis was 4.6 months (range: 1 to 12 months). The most common clinical sign was raised intracranial pressure (90%). Of the meningiomas diagnosed, 47% were convexity meningiomas while 24% were parasagittal and 19% were skull-base meningiomas; in two cases (9.5%) the location was intraventricular. The mean tumor diameter was 6.6. cm (range: 3 to 10. cm). A large cystic component was found in 24% of the cases. Surgery achieved a Simpson grade I resection in 47%; 62% of the tumors were grade I and 24% were grade II based on World Health Organization pathological classification. The mean follow-up period was 33 months (range: 6 to 120 months). The recurrence rate was 33%. Conclusion: Pediatric meningiomas are larger than those found in the adult population; there is a male predominance with high incidence of a cystic component and high-grade meningiomas, thus explaining the increased recurrence rate despite the multimodal treatment. © 2010 Elsevier Masson SAS.
Authors & Co-Authors
Lakhdar, Fayçal
Morocco, Rabat
Mohammed V University in Rabat
Arkha, Yasser
Morocco, Rabat
Mohammed V University in Rabat
El-Ouahabi, Abdessamad
Morocco, Rabat
Mohammed V University in Rabat
Melhaoui, A.
Morocco, Rabat
Mohammed V University in Rabat
Rifi, Loubna
Morocco, Rabat
Mohammed V University in Rabat
Derraz, Saïd
Morocco, Rabat
Mohammed V University in Rabat
El Khamlichi, Abdeslam
Morocco, Rabat
Mohammed V University in Rabat
Statistics
Citations: 35
Authors: 7
Affiliations: 1
Identifiers
Doi:
10.1016/j.neuchi.2010.05.008
Research Areas
Cancer
Health System And Policy
Maternal And Child Health
Study Design
Cross Sectional Study
Cohort Study
Participants Gender
Male
Female