Primitive adenocarcinoma of duodenum: Two cases report and review of literature

The primitive tumours of the duodenum are rare. They account for 0.04% of all the tumours. The adenocarcinoma is the histological type most frequent. Objective: The authors report two cases of primitive adenocarcinoma of the duodenum underlining the contribution of the imagery in the positive diagnosis and the extension of this pathology. Observations: Two patients of male sex respectively aged of 37 and 60 years, consulting for atypical pain and high digestive haemorrhagic. The fibroscopy with biopsy highlighted an adenocarcinoma. Ultrasound showed a circumferential parietal thickening in one case, the abdominal computed tomography revealed a tissuemass in both caseswith signs of the neighbour extension in one case. The treatmentwas palliative in one case. Conclusion: The positive diagnosis of the adenocarcinoma of duodenum rests on the fibroscopy. The imagery makes it possible to detect the small lesions and to contribute to the diagnosis in front of an atypical clinical signs or an insuperable tumour and to especially ensure the assessment of precise extension of this tumour with the development of the computed tomography and MRI. © 2009 Springer Verlag France.