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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Isolated Roux loop pancreaticojejunostomy versus pancreaticogastrostomy after pancreaticoduodenectomy: A prospective randomized study
HPB, Volume 16, No. 8, Year 2014
Notification
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Description
Objectives The optimal strategy for the reconstruction of the pancreas following pancreaticoduodenectomy (PD) is still debated. The aim of this study was to compare the outcomes of isolated Roux loop pancreaticojejunostomy (IRPJ) with those of pancreaticogastrostomy (PG) after PD. Methods Consecutive patients submitted to PD were randomized to either method of reconstruction. The primary outcome measure was the rate of postoperative pancreatic fistula (POPF). Secondary outcomes included operative time, day to resumption of oral feeding, postoperative morbidity and mortality, and exocrine and endocrine pancreatic functions. Results Ninety patients treated by PD were included in the study. The median total operative time was significantly longer in the IRPJ group (320 min versus 300 min; P = 0.047). Postoperative pancreatic fistula developed in nine of 45 patients in the IRPJ group and 10 of 45 patients in the PG group (P = 0.796). Seven IRPJ patients and four PG patients had POPF of type B or C (P = 0.710). Time to resumption of oral feeding was shorter in the IRPJ group (P = 0.03). Steatorrhea at 1 year was reported in nine of 42 IRPJ patients and 18 of 41 PG patients (P = 0.029). Albumin levels at 1 year were 3.6 g/dl in the IRPJ group and 3.3 g/dl in the PG group (P = 0.001). Conclusions Isolated Roux loop PJ was not associated with a lower rate of POPF, but was associated with a decrease in the incidence of postoperative steatorrhea. The technique allowed for early oral feeding and the maintenance of oral feeding even if POPF developed. © 2014 International Hepato-Pancreato-Biliary Association.
Authors & Co-Authors
El Nakeeb, Ayman M.
Egypt, Mansoura
Gastrointestinal Surgery Center
Hamdy, Emad
Egypt, Mansoura
Gastrointestinal Surgery Center
Sultan, Ahmad M.
Egypt, Mansoura
Gastrointestinal Surgery Center
Salah, Tarek
Egypt, Mansoura
Gastrointestinal Surgery Center
Askr, Waleed
Egypt, Mansoura
Gastrointestinal Surgery Center
Ezzat, Helmy
Egypt, Mansoura
Gastrointestinal Surgery Center
Said, Mohamed
Egypt, Mansoura
Gastrointestinal Surgery Center
Zeied, Mostaffa Abu
Egypt, Mansoura
Gastrointestinal Surgery Center
Abdallah, Talaat
Egypt, Mansoura
Gastrointestinal Surgery Center
Statistics
Citations: 90
Authors: 9
Affiliations: 1
Identifiers
Doi:
10.1111/hpb.12210
ISSN:
1365182X
e-ISSN:
14772574
Research Areas
Health System And Policy
Study Design
Cohort Study