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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Depression and CD4 cell count among persons with HIV infection in Uganda
AIDS and Behavior, Volume 10, No. SUPPL. 7, Year 2006
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Description
Despite the importance of mental illness and the high prevalence of HIV in Africa, few studies have documented depressive symptoms among HIV-infected persons in Africa. We assessed factors associated with depression among HIV-infected adults undergoing anti-retroviral eligibility screening in Eastern Uganda. Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale (CES-D). Univariate and multiple regression analyses were conducted to identify socio-demographic characteristics and disease-related factors associated with depression. Among 1017 HIV-infected participants assessed for depression, 47% (476/1017) reported depressive symptoms (CES-D ≥ 23). Adjusting for age, gender, education, and source of income, patients with CD4 counts <50 cells/μl were more likely to be depressed (odds ratio 2.34, 95% confidence interval, 1.39-3.93, P = 0.001). Women, participants >50 years, and those without an income source were more likely to be depressed. Depression was common among HIV-infected persons in rural Uganda and was associated with low CD4 cell counts. Appropriate screening and treatment for depression should be considered for comprehensive HIV care. © Springer Science+Business Media, Inc. 2006.
Authors & Co-Authors
Kaharuza, Frank M.
United States, Atlanta
Centers for Disease Control and Prevention
Bunnell, Rebecca E.
United States, Atlanta
Centers for Disease Control and Prevention
Uganda, Entebbe
Uganda Virus Research Institute
Moss, Susan
United States, Atlanta
Centers for Disease Control and Prevention
Purcell, David W.
United States, Atlanta
National Center for Hiv, Viral Hepatitis, Std, and tb Prevention
Bikaako-Kajura, Winnie
United States, Atlanta
Centers for Disease Control and Prevention
Wamai, Nafuna
United States, Atlanta
Centers for Disease Control and Prevention
Downing, Robert G.
United States, Atlanta
Centers for Disease Control and Prevention
Solberg, Peter
United States, San Francisco
University of California, San Francisco
Coutinho, Alex G.
Uganda, Kampala
Aids Support Organization Uganda
Mermin, Jonathan H.
United States, Atlanta
Centers for Disease Control and Prevention
Statistics
Citations: 211
Authors: 10
Affiliations: 5
Identifiers
Doi:
10.1007/s10461-006-9142-2
ISSN:
10907165
Research Areas
Infectious Diseases
Mental Health
Study Design
Cross Sectional Study
Case-Control Study
Study Locations
Uganda
Participants Gender
Female