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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Evaluation of syndromic management of sexually transmitted infections within the Kisumu Incidence Cohort Study
International Journal of STD and AIDS, Volume 25, No. 12, Year 2014
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Description
While laboratory aetiological diagnosis is considered the gold standard for diagnosis and management of sexually transmitted infections (STIs), syndromic management has been presented as a simplified and affordable approach for STI management in limited resource settings. STI signs and symptoms were collected using staff-administered computer-assisted personal interview and audio computer-assisted self-interview. Participants underwent a medical examination and laboratory testing for common STIs. The performance of syndromic management was assessed on the agreement between interviewing methods as well as accurate diagnosis. We screened 846 participants, of whom 88 (10.4%) received syndromic STI diagnosis while 272 (32.2%) received an aetiological diagnosis. Agreement between syndromic and aetiological diagnoses was very poor (overall kappa = 0.09). The most prevalent STI was herpes simplex virus type 2 and the percentage of persons with any STI was higher among women (48.6%) than men (15.6%, p < 0.0001). Agreement between audio computer-assisted self-interview and computer-assisted personal interview interviewing methods for syndromic diagnosis of STIs ranged from poor to good. Our findings suggest that syndromic management of STIs is not a sufficient tool for STI diagnosis in this setting; development and improvement of STI diagnostic capabilities through laboratory confirmation is needed in resource-limited settings. © The Author(s) 2014.
Authors & Co-Authors
Otieno, Fredrick Odhiambo
Kenya, Nairobi
Kenya Medical Research Institute
Ndivo, Richard
Kenya, Nairobi
Kenya Medical Research Institute
Oswago, Simon
Kenya, Nairobi
Kenya Medical Research Institute
Ondiek, Johnson
Kenya, Nairobi
Kenya Medical Research Institute
Pals, Sherri L.
United States, Atlanta
National Center for Infectious Diseases
McLellan-Lemal, Eleanor
United States, Atlanta
National Center for Infectious Diseases
Chen, Robert T. T.
United States, Atlanta
National Center for Infectious Diseases
Chege, Wairimu
United States, Atlanta
National Center for Infectious Diseases
Gray, Kristen Mahle
United States, Atlanta
National Center for Infectious Diseases
Statistics
Citations: 29
Authors: 9
Affiliations: 2
Identifiers
Doi:
10.1177/0956462414523260
ISSN:
09564624
Research Areas
Sexual And Reproductive Health
Study Design
Cohort Study
Study Approach
Quantitative
Participants Gender
Male
Female