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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Short report: Outpatient upper respiratory tract viral infections in children with malaria symptoms in Western Kenya
American Journal of Tropical Medicine and Hygiene, Volume 83, No. 5, Year 2010
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Description
A cross-sectional study was performed in children 5 through 10 years of age presenting to outpatient clinics in Nyanza Province, Kenya, in which nasal swab and blood specimens were collected during the high malaria transmission season. Patients presenting with malaria-like symptoms within 4 days of fever onset were enrolled in the study. Plasmodium parasitemia was determined by blood smear microscopy. Nasal swabs were screened for a panel of respiratory viruses by polymerase chain reaction. Influenza A, rhinoviruses, and other respiratory viruses were detected in 18%, 26%, and 12% of 197 specimens, respectively. Four of 36 patients with influenza A had a positive malaria blood slide, compared with 20 of 52 patients with rhinovirus. A significant burden of disease caused by influenza A in febrile children during the study period was observed, highlighting the need for further research into the burden of influenza disease in regions where malaria is holoendemic. Copyright © 2010 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Waitumbi, John Njenga
Kenya, Nairobi
Kenya Medical Research Institute
Kuypers, Jane M.
United States, Seattle
University of Washington
Anyona, Samuel B.
Kenya, Nairobi
Kenya Medical Research Institute
Koros, Joseph K.
Kenya, Nairobi
Kenya Medical Research Institute
Polhemus, Mark E.
Kenya, Nairobi
Kenya Medical Research Institute
Gerlach, Jay
United States, Seattle
Path Seattle
Steele, Matthew S.
United States, Seattle
Path Seattle
Englund, Janet A.
United States, Seattle
University of Washington
Neuzil, Kathleen Maletic
United States, Seattle
Path Seattle
Domingo, Gonzalo J.
United States, Seattle
Path Seattle
Statistics
Citations: 38
Authors: 10
Affiliations: 3
Identifiers
Doi:
10.4269/ajtmh.2010.10-0174
ISSN:
00029637
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Kenya