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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Immediate and one-year outcome of patients presenting with Acute Coronary Syndrome complicated by stroke: Findings from the 2
nd
Gulf Registry of Acute Coronary Events (Gulf RACE-2)
BMC Cardiovascular Disorders, Volume 12, Article 64, Year 2012
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Description
Background: Stroke is a potential complication of acute coronary syndrome (ACS). The aim of this study was to identify the prevalence, risk factors predisposing to stroke, in-hospital and 1-year mortality among patients presenting with ACS in the Middle East.Methods: For a period of 9 months in 2008 to 2009, 7,930 consecutive ACS patients were enrolled from 65 hospitals in 6 Middle East countries.Results: The prevalence of in-hospital stroke following ACS was 0.70%. Most cases were ST segment elevation MI-related (STEMI) and ischemic stroke in nature. Patients with in-hospital stroke were 5 years older than patients without stroke and were more likely to have hypertension (66% vs. 47.6%, P = 0.001). There were no differences between the two groups in regards to gender, other cardiovascular risk factors, or prior cardiovascular disease. Patients with stroke were more likely to present with atypical symptoms, advanced Killip class and less likely to be treated with evidence-based therapies. Independent predictors of stroke were hypertension, advanced killip class, ACS type -STEMI and cardiogenic shock. Stroke was associated with increased risk of in-hospital (39.3% vs. 4.3%) and one-year mortality (52% vs. 12.3%).Conclusion: There is low incidence of in-hospital stroke in Middle-Eastern patients presenting with ACS but with very high in-hospital and one-year mortality rates. Stroke patients were less likely to be appropriately treated with evidence-based therapy. Future work should be focused on reducing the risk and improving the outcome of this devastating complication. © 2012 Al Suwaidi et al.; licensee BioMed Central Ltd.
Authors & Co-Authors
Al Suwaidi, Jassim Mohd
Qatar, Doha
Hamad Medical Corporation
Qatar, Doha
Hamad General Hospital
al-Habib, Khalid F.
Saudi Arabia, Riyadh
King Khalid University Hospital
Asaad, Nidal Ahmad
Qatar, Doha
Hamad Medical Corporation
Singh, Rajvir R.
Qatar, Doha
Hamad Medical Corporation
Hersi, Ahmad Salah
Saudi Arabia, Riyadh
King Khalid University Hospital
Al Falaeh, Husam
Saudi Arabia, Riyadh
Security Forces Hospital Program Riyadh
al-Saif, Shukri M.
Saudi Arabia, Dammam
Saud Albabtain Cardiac Center
Al-Motarreb, Ahmed Lotf
Yemen, Sana's
Sana's University
Al-Mahmeed, Wael Abdulrahman R.
Unknown Affiliation
Sulaiman, Kadhim J.
Oman, Muscat
Royal Hospital
Amin, Haitham
Bahrain, West Riffa
Bahrain Defence Force Royal Medical Services
Al-Lawati, Jawad Ahmed
Oman, Muscat
Ministry of Health Oman
Al-Sagheer, Norah Q.
Yemen, Sana'a
Al-thawra Hospital
Alsheikh-Ali, Alawi A.
United States, Boston
Tufts University School of Medicine
Salam, A. M.
Qatar, Doha
Hamad Medical Corporation
Statistics
Citations: 18
Authors: 15
Affiliations: 11
Identifiers
Doi:
10.1186/1471-2261-12-64
e-ISSN:
14712261
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Design
Cross Sectional Study
Cohort Study