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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Lipid and hematological parameters in hyperleptinemic healthy Arab male youth in Jordan
Pakistan Journal of Biological Sciences, Volume 14, No. 5, Year 2011
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Description
To analyze the influence of hyperleptinemia on fasting lipid and hematological parameters in healthy Arab male youth in Jordan, this cross-sectional study was carried out in April 2009 on a sample of 120 students aged 18-24 years. Subjects were stratified by fasting leptin into two groups (control, <12.7 ng mL_1 vs. hyperleptenimic, e_<12.7 ngmL-1) and BME (normal weight, <25 kg m-2 vs. overweight/obese, BME e_<25 kg m-2). Fasting serum leptin, blood glucose, lipid profile and hematological parameters values were determined by standard kit methods. Mean serum leptin concentrations were more than five times as high in hyperleptenemic subjects than in control subjects (p<0.001). Compared with control group, significant elevations (p<0.01) were observed in the means total cholesterol, LDL cholesterol and triglyceride levels of hyperleptenemic group whereas no significant differences was detected in HDL-cholesterol. Except the changes of WBC count, MCH and slightly MCHC, there were no differences between both groups in any other term of hematological parameters. In conclusion, changes in lipid variables and some hematological parameters may increase plasma viscosity as a step during atherosclerosis pathogenesis in male youth at risk for dyslipidemia and cardiovascular diseases. Thus, hyperleptinemia could be a useful index in identifying healthy youth male subjects but this hypothesis needs further investigation. © 2011 Asian Network for Scientific Information.
Authors & Co-Authors
Abu-Samak, Mahmoud
Saudi Arabia, Abha
Al-ghad College for Health Sciences
Yousef, Al Motassem F.
Jordan, Amman
The University of Jordan
Al-Jarie, Ahmed A.
Saudi Arabia, Abha
Al-ghad College for Health Sciences
Al-Matubsi, H. Y.Hisham Y.
Jordan, Amman
Applied Science Private University
Abu-zaiton, Ahmed
Jordan, Ma'an
Al-hussein Bin Talal University
Al-Quraan, Mamoun
Saudi Arabia, Abha
Al-ghad College for Health Sciences
Khuzaie, Rula
Jordan, Amman
Applied Science Private University
Statistics
Citations: 7
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.3923/pjbs.2011.344.350
e-ISSN:
18125735
Research Areas
Noncommunicable Diseases
Study Design
Randomised Control Trial
Cross Sectional Study
Study Approach
Quantitative
Participants Gender
Male