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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Comparative study between biofeedback retraining and botulinum neurotoxin in the treatment of anismus patients
International Journal of Colorectal Disease, Volume 24, No. 1, Year 2009
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Description
Purpose: Anismus is a significant cause of chronic constipation. This study came to revive the results of BFB training and BTX-A injection in the treatment of anismus patients. Materials and methods: Forty-eight patients with anismus (33 women; mean age 39.6 ± 15.9) were included in this study. All patients fulfilled Rome II criteria for functional constipation. All patients underwent anorectal manometry, balloon expulsion test, defecography, and electromyography (EMG) activity of the EAS. All patients had non-relaxing puborectalis muscle. The patients were randomized into two groups. Group I patients received biofeedback therapy, two times per week for about 1 month. Group II patients were injected with BTX-A. Follow-up was conducted weekly in the first month then monthly for about 1 year. Results: In the BFB training group, three patients quit before the end of sessions with no improvement; initial improvement was recorded in 12 patients (50%) while long-term success was recorded in six patients (25%). In the BTX-A group, clinical improvement was recorded in 17 patients (70.83%), but the improvement persisted only in eight patients (33.3%). There is a significant difference between BTX-A group and BFB group regarding the initial success, but this significant difference disappeared at the end of follow-up. Manometric relaxation was achieved significantly post-BFB and post-BTX-A injection with no significant difference between the two groups. Conclusions: Biofeedback training has a limited therapeutic effect on patients suffering from anismus. BTX-A injection seems to be successful for temporary treatment of anismus. © Springer-Verlag 2008.
Authors & Co-Authors
Farid, Mohamed E.
Egypt, Mansoura
Faculty of Medicine
Monem, Hisham Abd
Egypt, Mansoura
Faculty of Medicine
Omar, Waleed H.
Egypt, Mansoura
Faculty of Medicine
El Nakeeb, Ayman M.
Egypt, Mansoura
Faculty of Medicine
Fikry, Amir
Egypt, Mansoura
Faculty of Medicine
Youssef, Tamer Fady
Egypt, Mansoura
Faculty of Medicine
Yousef, Mohamed
Egypt, Mansoura
Faculty of Medicine
Elbanna, Hosam Ghazy
Egypt, Mansoura
Faculty of Medicine
Fouda, El Yamani
Egypt, Mansoura
Faculty of Medicine
Metwally, Teto
Egypt, Mansoura
Faculty of Medicine
Khafagy, Wael W.
Egypt, Mansoura
Faculty of Medicine
Ahmed, Sabry
Egypt, Mansoura
Faculty of Medicine
Awady, Saleh El
Egypt, Mansoura
Faculty of Medicine
Morshed, Mosaad M.
Egypt, Mansoura
Faculty of Medicine
Lithy, Ramadan
Egypt, Mansoura
Faculty of Medicine
Statistics
Citations: 80
Authors: 15
Affiliations: 1
Identifiers
Doi:
10.1007/s00384-008-0567-0
ISSN:
01791958
Study Design
Cohort Study
Participants Gender
Female