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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Acute renal failure and pregnancy: A seventeen-year experience of a Tunisian intensive care unit
Renal Failure, Volume 35, No. 9, Year 2013
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Description
Purpose: To describe the epidemiologic features of acute renal failure related to pregnancy (PRARF) and to evaluate its prognostic impact. Methods: Retrospective study conducted in a Tunisian intensive care unit over a period of 17 years (1995-2011). Women were included if they were more than 20 weeks pregnant and were admitted to the ICU during pregnancy or immediately (<7 d) post partum. PRARF was defined by a serum creatinine level >0.8 mg/dL and was classified as mild (0.9 to 1.4 mg/dL), moderate (1.5 to 2.9 mg/dL) or severe (>3 mg/dL). Results: Five hundred and fifty patients were included. Mean age was 31 ± 6 years. Mean SOFA score was 4 ± 3. PRARF was diagnosed in 313 patients (56.9%). ARF was mild in 215 cases (39.1%), moderate in 65 cases (11.8%) and severe in 33 cases (6%). Main causes leading to this complication were preeclampsia (66.5%) and acute hemorrhage (27.8%). Only two patients (0.4%) developed chronic renal failure and needed long-term dialysis. Patients who developed this complication had higher SOFA score (4.7 ± 3.5 vs. 3.2 ± 2.1; p < 0.001). Thirty-three patients (6%) died in the ICU. The rate of ICU mortality was significantly higher in patients with PRARF (9.3 vs. 1.7%; p < 0.001). Conclusions: PRARF is associated with higher mortality. Thus, appropriate monitoring of pregnancies is needed in order to prevent its onset by an early and prompt management of the underlying risk factors. © 2013 Informa Healthcare USA, Inc.
Authors & Co-Authors
Bouaziz, Mounir
Tunisia, Medenine
Habib Bourguiba University Hospital
Chaari, Anis N.
Tunisia, Medenine
Habib Bourguiba University Hospital
Turki, Olfa
Tunisia, Medenine
Habib Bourguiba University Hospital
Dammak, Hassan
Tunisia, Medenine
Habib Bourguiba University Hospital
Chelly, Hédi E.
Tunisia, Medenine
Habib Bourguiba University Hospital
Ammar, Rania
Tunisia, Medenine
Habib Bourguiba University Hospital
Nasri, Abdennour
Tunisia, Medenine
Habib Bourguiba University Hospital
Ben Algia, Najla
Tunisia, Medenine
Habib Bourguiba University Hospital
Bahloul, Mabrouk
Tunisia, Medenine
Habib Bourguiba University Hospital
Ben Hamida, Chokri
Tunisia, Medenine
Habib Bourguiba University Hospital
Statistics
Citations: 17
Authors: 10
Affiliations: 1
Identifiers
Doi:
10.3109/0886022X.2013.819767
ISSN:
0886022X
e-ISSN:
15256049
Research Areas
Health System And Policy
Maternal And Child Health
Noncommunicable Diseases
Sexual And Reproductive Health
Study Design
Cohort Study
Participants Gender
Female