Publication Details

AFRICAN RESEARCH NEXUS

SHINING A SPOTLIGHT ON AFRICAN RESEARCH

materials science

Esterase- and pH-responsive poly(β-amino ester)-capped mesoporous silica nanoparticles for drug delivery

Nanoscale, Volume 7, No. 16, Year 2015

Gating of mesoporous silica nanoparticles (MSNs) with the stimuli-responsive poly(β-amino ester) has been achieved. This hybrid nanocarrier releases doxorubicin (DOX) under acidic conditions or in the presence of porcine liver esterase. The DOX loaded poly(β-amino ester)-capped MSNs reduce cell viability when tested on MDA-MB-231 human breast cancer cells.

Statistics
Citations: 59
Authors: 14
Affiliations: 4
Identifiers
Doi: 10.1039/c4nr07443b
ISSN: 20403364
e-ISSN: 20403372
Research Areas
Cancer

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