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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Effectiveness of dried Carica papaya seeds against human intestinal parasitosis: A pilot study
Journal of Medicinal Food, Volume 10, No. 1, Year 2007
Notification
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Description
The tropical fruit Carica papaya and its seeds have proven antihelminthic and anti-amoebic activities. To determine the effectiveness of air-dried C. papaya seeds on human intestinal parasitosis, 60 asymptomatic Nigerian children with stool microscopic evidence of intestinal parasites received immediate doses (20 mL) of either an elixir composed with air-dried C. papaya seeds and honey (CPH) or honey alone (placebo) in two randomized treatment groups. Repeat stool microscopic examinations were conducted 7 days postintervention for intestinal parasites. Significantly more subjects given CPH elixir than those given honey had their stools cleared of parasites [23 of 30 (76.7%) vs. five of 30 (16.7%); z = 4.40, P = .0000109]. There were no harmful effects. The stool clearance rate for the various types of parasites encountered was between 71.4% and 100% following CPH elixir treatment compared with 0-15.4% with honey. Thus, air-dried C. papaya seeds are efficacious in treating human intestinal parasites and without significant side effects. Their consumption offers a cheap, natural, harmless, readily available monotherapy and preventive strategy against intestinal parasitosis, especially in tropical communities. Further and large-scale intervention studies to compare C. papaya with standard antiparasitic preparation are desirous. © Mary Ann Liebert, Inc. and Korean Society of Food Science and Nutrition.
Authors & Co-Authors
Okeniyi, John Akintunde
Nigeria, Ife
Obafemi Awolowo University
Nigeria, Ilesa
Wesley Guild Hospital
Ogunlesi, Tinuade Adetutu
Nigeria, Ilesa
Wesley Guild Hospital
Oyelami, Oyeku Akibu
Nigeria, Ife
Obafemi Awolowo University
Adeyemi, L. A.
Nigeria, Ilesa
Wesley Guild Hospital
Statistics
Citations: 128
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.1089/jmf.2005.065
ISSN:
1096620X
Research Areas
Environmental
Food Security
Maternal And Child Health
Study Design
Randomised Control Trial