Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Clinical presentation and outcome of retinoblastoma among children treated at the National Cancer Institute (NCI) in Gezira, Sudan: A single institution experience
Ophthalmic Genetics, Volume 32, No. 2, Year 2011
Notification
URL copied to clipboard!
Description
Background: Retinoblastoma (RB) is a rare and unique cancer that affects the eyes of very young children. There are few reports on RB in Sudan. Materials and Methods: We performed a retrospective study of data from patients diagnosed with retinoblastoma between January 1999 and December 2009 at the National Cancer Institute in Gezira (NCI-Gezira). Results: Of the 519 cases of childhood cancer treated at NCI-Gezira during the study period, 25 (4.8%) were retinoblastoma. Of these 25 patients with retinoblastoma, there were 13 boys and 19 cases were unilateral. The median age at diagnosis was 36 months (range, 8-60 months). The disease was localized in 9 patients, regional in 5 patients, and metastatic in 11 patients. The most frequent symptoms were enlarged eye (n = 14) and leukocoria (n = 8). Nine patients (36%) have been lost to follow-up; 9 were alive at last follow-up (7 in remission, 2 progressed); and 7 have died (5 from disease and 2 from unrelated causes). Twenty-two eyes were enucleated in 16 patients (6 bilateral and 10 unilateral). Pathologic examination of the enucleated eyes could only be completed in 11 patients. Diagnostic imaging in the form of computerized tomography scans or ultrasonography of the brain and orbit was done for 10 patients (40%). Conclusions: Although these findings are not surprising, and similar to reports from other developing countries, we hope our work will provide a foundation for strategies to improve outcome for retinoblastoma in our center such as proper training, public awareness, team approach, and twinning. © 2011 Informa Healthcare USA, Inc.
Authors & Co-Authors
Ali, Amel A.E.
Sudan, Wad Medani
University of Gezira
Elsheikh, Sara M.A.
Sudan, Wad Medani
University of Gezira
Elhaj, Ahmed Mohammed
Sudan, Wad Medani
University of Gezira
Osman, Nada
Sudan, Wad Medani
University of Gezira
Abuidris, Dafalla Omer
Sudan, Wad Medani
University of Gezira
Eltayeb, Elgaylani Abdalla
Sudan, Wad Medani
University of Gezira
Mahgoub, Maha
Sudan
Ophthalmology Hospital Ministry of Health
Hamdoun, Anas
Sudan, Wad Medani
University of Gezira
Babiker, Mohamed Mousa
Sudan, Wad Medani
University of Gezira
Mohamedani, Ahmed Abdalla
Sudan, Wad Medani
University of Gezira
Elwali, Nasr Eldin
Sudan, Wad Medani
University of Gezira
Qaddoumi, Ibrahim A.
United States, Memphis
St. Jude Children's Research Hospital
Statistics
Citations: 38
Authors: 12
Affiliations: 3
Identifiers
Doi:
10.3109/13816810.2010.546822
e-ISSN:
17445094
Research Areas
Cancer
Health System And Policy
Maternal And Child Health
Study Design
Cohort Study
Study Locations
Sudan
Participants Gender
Male