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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Interobserver variability of optic disk variables measured by confocal scanning laser tomography
American Journal of Ophthalmology, Volume 132, No. 1, Year 2001
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Description
PURPOSE: To assess the interobserver variation of confocal laser scanning tomographic measurements of the optic nerve head and to address the question of whether the addition of clinical optic disk photographs is helpful in outlining the optic disk margin and in reducing the observer-related variation of the measurements. PATIENTS AND METHODS: Optic disk variables for 16 eyes of 16 patients with glaucoma, generated by confocal laser scanning laser tomography (Heidelberg Retina Tomograph), were independently evaluated by four experienced glaucoma specialists, and the interobserver variability was calculated. A second separate review by the same observers included the use of clinical stereoscopic color optic nerve head photographs to aid definition of the optic disk margin. RESULTS: Optic disk parameters with the smallest interobserver variation were cup shape measure, maximum cup depth, height variation contour, and mean height contour. The intraobserver variation of these parameters did not increase when clinical optic disk slides were additionally available. Parameters with the highest interobserver variation were volume below surface, volume below reference, volume above surface, and volume above reference. The observer variation of these optic disk parameters increased significantly for two of the four examiners when clinical optic disk slides were additionally available for outlining the optic disk margin. CONCLUSION: Confocal laser scanning tomography of the optic nerve head can be improved significantly if clinical optic disk photographs are additionally available to help in outlining the optic disk margin. Because interobserver variation in the tomographic optic disk measurements can be significant, even if experienced observer are involved, tomographic optic disk measurements may be centralized in reading centers in the case of multicenter studies. Copyright © 2001 Elsevier Science Inc.
Authors & Co-Authors
Courtright, Paul D.
Canada, Vancouver
The University of British Columbia
Caprioli, Joseph
United States, Los Angeles
University of California, Los Angeles
Jonas, Jost Bruno
Germany, Heidelberg
Universität Heidelberg
Weinreb, Robert N.
United States, La Jolla
University of California, San Diego
Zangwill, Linda M.
United States, La Jolla
University of California, San Diego
Statistics
Citations: 52
Authors: 5
Affiliations: 7
Identifiers
Doi:
10.1016/S0002-9394(01)00938-2
ISSN:
00029394
Research Areas
Health System And Policy