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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Biosynthesis of silver nanoparticles from Staphylococcus aureus and its antimicrobial activity against MRSA and MRSE
Nanomedicine: Nanotechnology, Biology, and Medicine, Volume 5, No. 4, Year 2009
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Description
Silver bionanoparticles (AgNPs) have been known to have inhibitory and bactericidal effects. Resistance to antimicrobial agents by pathogenic bacteria has emerged in recent years and is a major health problem. This report focuses on the synthesis of metallic bionanoparticles of silver using a reduction of aqueous Ag+ ion with the culture supernatants of Staphylococcus aureus. The bioreduction of the Ag+ ions in the solution was monitored in the aqueous component and the spectrum of the solution measured through ultraviolet-visible spectrophotometry and characterized by atomic force microscopy. The AgNPs were evaluated for their antimicrobial activities against different pathogenic organisms. The most sensitive antimicrobial activity has been observed against methicillin-resistant S. aureus followed by methicillin-resistant Staphylococcus epidermidis and Streptococcus pyogenes, whereas only moderate antimicrobial activity was seen against Salmonella typhi and Klebsiella pneumoniae. From the Clinical Editor: Silver bionanoparticles (AgNPs) were evaluated for their antimicrobial activities against different pathogenic organisms. The most sensitive antimicrobial activity has been observed against methicillin-resistant S. aureus followed by methicillin-resistant Staphylococcus epidermidis and Streptococcus pyogenes, whereas only moderate antimicrobial activity was seen against Salmonella typhi and Klebsiella pneumoniae. © 2009.
Authors & Co-Authors
Saravanan, Muthupandian
India, Kattankulathur
Srm Institute of Science and Technology
Statistics
Citations: 567
Authors: 1
Affiliations: 2
Identifiers
Doi:
10.1016/j.nano.2009.01.012
ISSN:
15499634
Research Areas
Infectious Diseases