Parenchymal splenic metastasis from ovarian cancer: A report of two cases and literature review

Aim: We report two cases of splenic metastasis from ovarian cancer. Background: Parenchymal splenic metastasis from ovarian cancer is rarely encountered. Case description: Two cases of ovarian serous carcinoma presented by isolated recurrent parenchymal splenic metastasis that was managed by splenectomy as secondary cytoreductive surgery. Conclusion: Thorough follow-up of ovarian cancer cases including careful clinical examination, computed tomography (CT), and tumor markers assessment, when clinically indicated, can early detect any recurrence events even isolated splenic recurrence. Clinical significance: Although being rare, parenchymal splenic metastasis from ovarian cancer should be suspected in advanced stage ovarian cancer.