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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Prevention of malaria during pregnancy: Assessing the effect of the distribution of IPTp through the national policy in Benin
American Journal of Tropical Medicine and Hygiene, Volume 84, No. 2, Year 2011
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Description
The efficiency of malaria prevention during pregnancy was compared between three studies in Benin for malaria infection of the placenta (MIP) and low birth weight (LBW). The first was carried out when chloroquine prophylaxis was still recommended, the second was an intermittent preventive treatment in pregnancy (IPTp) clinical trial comparing sulfadoxine pyrimetamine (SP) versus mefloquine, and the third was an observational study after SP-IPTp national implementation. We showed an association between the use of IPTp and the reduction of LBW (10% with national IPTp and 8.7% in IPTp trial versus 15.7% in pre-trial study). The effect on MIP was better in the trial (2.9% versus 11.2% and 16.7% for national IPTp and pre-trial studies, respectively). In spite of a good overall compliance with the national IPTp (with 84% of women taking at least one dose of SP), there are still failures in adherence to the directly observed therapy (DOT) scheme and needs for better training of health staff. Copyright © 2011 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Le Port, Agnes
France, Paris
Université Paris Cité
Cottrell, Gilles
Unknown Affiliation
Dechavanne, Célia
France, Paris
Université Paris Cité
Briand, Valérie
France, Paris
Université Paris Cité
Bouraïma, Aziz
Benin, Cotonou
University of Abomey-calavi
Guerra, José
France, Paris
Université Paris Cité
Choudat, Isabelle
France, Paris
Université Paris Cité
Massougbodji, Achille
Benin, Cotonou
Université de Cotonou
Fayomi, Benjamin Eboum
Benin, Cotonou
University of Abomey-calavi
Migot-Nabias, Florence
France, Paris
Université Paris Cité
Garcia, André
France, Paris
Université Paris Cité
Cot, Michel
France, Paris
Université Paris Cité
Statistics
Citations: 26
Authors: 12
Affiliations: 3
Identifiers
Doi:
10.4269/ajtmh.2011.10-0319
ISSN:
00029637
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Sexual And Reproductive Health
Study Locations
Benin
Participants Gender
Female