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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Multilocus sequence typing (MLST) analysis of Vibrio cholerae O1 El Tor isolates from Mozambique that harbour the classical CTX prophage
Journal of Medical Microbiology, Volume 55, No. 2, Year 2006
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Description
Vibrio cholerae O1 isolates belonging to the Ogawa serotype, El Tor biotype, harbouring the classical CTX prophage were first isolated in Mozambique in 2004. Multilocus sequence typing (MLST) analysis using nine genetic loci showed that the Mozambique isolates have the same sequence type (ST) as O1 El Tor N16961, a representative of the current seventh cholera pandemic. Analysis of the CTX prophage in the Mozambique isolates indicated that there is one type of rstR in these isolates: the classical CTX prophage. It was also found that the ctxB-rstR-rstA-rstB-phs-cep fragment was PCR-amplified from these isolates, which indicates the presence of a tandem repeat of the classical CTX prophage in the genome of the Mozambique isolates. The possible origin of these isolates and the presence of the tandem repeat of the classical prophage in them implicate the presence of the classical CTX phage. © 2006 SGM.
Authors & Co-Authors
Lee, Jehee
South Korea, Seoul
International Vaccine Institute, Seoul
South Korea, Seoul
Seoul National University
Han, Kyung Ho
South Korea, Seoul
International Vaccine Institute, Seoul
Choi, Seon-young
South Korea, Seoul
International Vaccine Institute, Seoul
South Korea, Seoul
Seoul National University
Lucas, Marcelino E.S.
Mozambique, Maputo
Ministry of Health Mozambique
Mondlane, Catarina
Mozambique
Centro de Higiene Ambiental e Exames Medicos
Ansaruzzaman, Mohammad
Bangladesh, Dhaka
International Centre for Diarrhoeal Disease Research Bangladesh
Nair, Gopinath Balakrish
Bangladesh, Dhaka
International Centre for Diarrhoeal Disease Research Bangladesh
Sack, David Allen
Bangladesh, Dhaka
International Centre for Diarrhoeal Disease Research Bangladesh
Von-Seidlein, Lorenz
South Korea, Seoul
International Vaccine Institute, Seoul
Clemens, John David
South Korea, Seoul
International Vaccine Institute, Seoul
Song, Manki
South Korea, Seoul
International Vaccine Institute, Seoul
Chun, Jongsik
South Korea, Seoul
International Vaccine Institute, Seoul
South Korea, Seoul
Seoul National University
Kim, Dong-wook
South Korea, Seoul
International Vaccine Institute, Seoul
Statistics
Citations: 71
Authors: 13
Affiliations: 5
Identifiers
Doi:
10.1099/jmm.0.46287-0
ISSN:
00222615
Research Areas
Genetics And Genomics
Infectious Diseases
Study Locations
Mozambique