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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Inflammation and nutritional science for programs/policies and interpretation of research evidence (INSPIRE)
Journal of Nutrition, Volume 145, No. 5, Year 2015
Notification
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Description
An increasing recognition has emerged of the complexities of the global health agenda-specifically, the collision of infections and noncommunicable diseases and the dual burden of over- and undernutrition. Of particular practical concern are both 1) the need for a better understanding of the bidirectional relations between nutritional status and the development and function of the immune and inflammatory response and 2) the specific impact of the inflammatory response on the selection, use, and interpretation of nutrient biomarkers. The goal of the Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE) is to provide guidance for those users represented by the global food and nutrition enterprise. These include researchers (bench and clinical), clinicians providing care/treatment, those developing and evaluating programs/interventions at scale, and those responsible for generating evidence-based policy. The INSPIRE process included convening 5 thematic working groups (WGs) charged with developing summary reports around the following issues: 1) basic overview of the interactions between nutrition, immune function, and the inflammatory response; 2) examination of the evidence regarding the impact of nutrition on immune function and inflammation; 3) evaluation of the impact of inflammation and clinical conditions (acute and chronic) on nutrition; 4) examination of existing and potential new approaches to account for the impact of inflammation on biomarker interpretation and use; and 5) the presentation of new approaches to the study of these relations. EachWGwas tasked with synthesizing a summary of the evidence for each of these topics and delineating the remaining gaps in our knowledge. This review consists of a summary of the INSPIRE workshop and the WG deliberations. © 2015 American Society for Nutrition.
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC4448820/bin/supp_145_5_1039S__index.html
https://efashare.b-cdn.net/share/pmc/articles/PMC4448820/bin/jn.114.194571_nutrition194571SupplementaryData1.pdf
Authors & Co-Authors
Raiten, Daniel J.
United States, Bethesda
National Institutes of Health Nih
Sakr-Ashour, Fayrouz A.
United States, Bethesda
National Institutes of Health Nih
Ross, A. Catharine
United States, University Park
Pennsylvania State University
Meydani, S. N.
United States, Medford
Tufts University
Stephensen, Charles Bolt
United States, Washington, D.c.
United States Department of Agriculture
Brabin, Bernard J.
United Kingdom, Liverpool
Liverpool School of Tropical Medicine
Netherlands, Amsterdam
Amsterdam Umc - University of Amsterdam
Suchdev, Parminder S.
United States, Atlanta
Emory University
Ahmed, Tahmeed J.
Unknown Affiliation
Allen, Lindsay Helen
Unknown Affiliation
Brindle, Eleanor
Unknown Affiliation
Brown, Kenneth H.
Unknown Affiliation
Calder, Philip C.
Unknown Affiliation
Checkley, William N.
Unknown Affiliation
Coles, Christian L.
Unknown Affiliation
Esamai, Fabian O.
Unknown Affiliation
Friis, Henrik M.U.
Unknown Affiliation
Guerrant, Richard Littleton
Unknown Affiliation
Hellerstein, Marc K.
Unknown Affiliation
Hunt, Janet R.
Unknown Affiliation
King, J. C.
Unknown Affiliation
Northrop-Clewes, Christine A.
Unknown Affiliation
Pfeiffer, Christine M.
Unknown Affiliation
Prentice, Andrew M.
Unknown Affiliation
Ramírez-Zea, Manuel
Unknown Affiliation
Rink, Lothar
Unknown Affiliation
Benn, Christine Stabell
Unknown Affiliation
Sullivan, Kevin M.
Unknown Affiliation
Thurnham, David I.
Unknown Affiliation
van der Ven, André J.A.M.
Unknown Affiliation
Statistics
Citations: 163
Authors: 29
Affiliations: 9
Identifiers
Doi:
10.3945/jn.114.194571
ISSN:
00223166
Research Areas
Food Security
Health System And Policy
Noncommunicable Diseases