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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Rift valley fever seroprevalence in Coastal Kenya
American Journal of Tropical Medicine and Hygiene, Volume 97, No. 1, Year 2017
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Description
Rift Valley fever virus (RVFV) causes severe disease in both animals and humans, resulting in significant economic and public health damages. The objective of this study was to measure RVFV seroprevalence in six coastal Kenyan villages between 2009 and 2011, and characterize individual-, household-, and community-level risk factors for prior RVFV exposure. Sera were tested for anti-RVFV IgG via enzyme-linked immunosorbent assay. Overall, 51 (1.8%; confidence interval [CI95] 1.3-2.3) of 2,871 samples were seropositive for RVFV. Seroprevalence differed significantly among villages, and was highest in Jego Village (18/300; 6.0%; CI95 3.6-9.3) and lowest in Magodzoni (0/248). Adults were more likely to be seropositive than children (P < 0.001). Seropositive subjects were less likely to own land or a motor vehicle (P < 0.01), suggesting exposure is associated with lower socioeconomic standing (P = 0.03). RVFV exposure appears to be low in coastal Kenya, although with some variability among villages. © 2017 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Grossi-Soyster, Elysse Noel
United States, Stanford
Stanford University School of Medicine
Banda, Tamara
United States, Oakland
Children's Hospital Oakland Research Institute
Teng, Crystal Y.
United States, Oakland
Children's Hospital Oakland Research Institute
Muchiri, Eric M.
Kenya, Nairobi
Ministry of Health Nairobi
Mungai, Peter L.
Kenya, Nairobi
Ministry of Health Nairobi
Mutuku, Francis Maluki
Kenya, Nairobi
Ministry of Health Nairobi
United States, Atlanta
Emory University
Gildengorin, Ginny L.
United States, Oakland
Children's Hospital Oakland Research Institute
Kitron, Uriel D.
United States, Atlanta
Emory University
King, Charles Harding
United States, Cleveland
Case Western Reserve University
LaBeaud, Angelle Désirée
United States, Stanford
Stanford University School of Medicine
United States, Oakland
Children's Hospital Oakland Research Institute
Statistics
Citations: 18
Authors: 10
Affiliations: 5
Identifiers
Doi:
10.4269/ajtmh.17-0104
ISSN:
00029637
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Locations
Kenya