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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
HIV-1 effects on neuropsychological performance in a resource-limited country, Zambia
AIDS and Behavior, Volume 15, No. 8, Year 2011
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Description
Zambia has substantially been affected by the HIV/AIDS epidemic with prevalence rates at 14% in a population estimated at 12 million. Yet, the extent of HIVassociated neurocognitive disorders (HAND) in this population remains to be clearly understood.Aseries of culturally appropriate neuropsychological (NP) assessments [International HIV Dementia Scale (IHDS), Color Trails Test 1 and 2, Grooved pegboard Test, and Time Gait Test] were used to test the effects of HIV on NP performance of HIV seropositive and seronegative individuals. Twenty-two percent HIV positive individuals ARV naïve met the criteria for IHDSdefined NP impairment. Gender significantly influenced the performance on NP tests with females performing more poorly compared to males. Larger studies that will accommodate gender differences and age are necessary to generate appropriate norms in Zambia in order to better assess the prevalence of HAND in the developing country setting. © Springer Science+Business Media, LLC 2011.
Authors & Co-Authors
Holguin, Adelina
United States, Lincoln
School of Biological Sciences
Banda, Mwanza
Zambia, Lusaka
University Teaching Hospital Lusaka
Willen, Elizabeth J.
United States, Miami
University of Miami Leonard M. Miller School of Medicine
Malama, Costantine
United States, Lincoln
School of Biological Sciences
Chiyeñu, Kaseya O.R.
Zambia, Lusaka
University Teaching Hospital Lusaka
Mudenda, Victor C.
Zambia, Lusaka
University Teaching Hospital Lusaka
Wood, Charles
United States, Lincoln
School of Biological Sciences
Statistics
Citations: 7
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1007/s10461-011-9988-9
ISSN:
10907165
Research Areas
Infectious Diseases
Mental Health
Study Design
Cross Sectional Study
Study Locations
Zambia
Participants Gender
Female