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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
A quality-effects model for meta-analysis
Epidemiology, Volume 19, No. 1, Year 2008
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Description
We introduce a quality-effects approach that combines evidence from a series of trials comparing 2 interventions. This approach incorporates the heterogeneity of effects in the analysis of the overall interventional efficacy. However, unlike the random-effects model based on observed between-trial heterogeneity, we suggest adjustment based on measured methodological heterogeneity between studies. We propose a simple noniterative procedure for computing the combined effect size under this model and suggest that this could represent a more convincing alternative to the random effects model. © 2008 Lippincott Williams & Wilkins, Inc.
Authors & Co-Authors
Doi, Suhail A.
Kuwait, Safat
Mubarak Al-kabeer Hospital
Kuwait, Kuwait City
Kuwait University
Thalib, Lukman
Kuwait, Kuwait City
Kuwait University
Statistics
Citations: 228
Authors: 2
Affiliations: 2
Identifiers
Doi:
10.1097/EDE.0b013e31815c24e7
ISSN:
10443983
Research Areas
Genetics And Genomics
Study Approach
Systematic review