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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Guillain-Barré syndrome as a prominent cause of childhood acute flaccid paralysis in post polio eradication era in Egypt
European Journal of Paediatric Neurology, Volume 15, No. 3, Year 2011
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Description
Guillain-Barré syndrome often follows an antecedent gastrointestinal or respiratory illness but, in rare cases, follows vaccination. This study was conducted to identify preceding events, demographic, clinical characteristics and prognostic factors of childhood Guillain-Barré syndrome after post-poliomyelitis eradication era in Egypt. This is a prospective study of all children with GBS (no = 50) admitted to pediatric Cairo University Hospital between January 2006 and June 2007 (70.42% of all acute flaccid paralysis patients during this period). Upper respiratory infection was the most common preceding event (24%) while only 4 patients (8%) reported antecedent oral polio vaccine. Motor deficit was frequent and severe (quadriparesis in 92% and paraparesis in 8%). Autonomic dysfunction was recorded in 32% of patients. Forty two percent of patients had poor outcome with 16% deaths. Presence of severe disability on admission and on nadir, cranial nerve affection or the need for mechanical ventilator were found to be significant predictors for poor outcome. © 2010 European Paediatric Neurology Society.
Authors & Co-Authors
Halawa, Eman Fawzy
Egypt, Cairo
Faculty of Medicine
Ahmed, Dalia
Egypt, Cairo
Faculty of Medicine
Nada, Mona Af
Egypt, Cairo
Faculty of Medicine
Statistics
Citations: 19
Authors: 3
Affiliations: 1
Identifiers
Doi:
10.1016/j.ejpn.2010.11.008
ISSN:
10903798
Research Areas
Disability
Health System And Policy
Maternal And Child Health
Study Design
Cohort Study
Study Locations
Egypt