Curatively resected gastric adenocarcinomas: A multivariate study of prognostic factors; [ADENOCARCINOMES GASTRIQUES RESEQUES CURATIVEMENT. ANALYSE MULTIFACTORIELLE DES FACTEURS PRONOSTIQUES]
Gastroenterologie Clinique et Biologique, Volume 12, No. 10, Year 1988
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One hundred and twelve curatively resected gastric adenocarcinomas were studied retrospectively to appreciate the survival factors. Twenty different criteria (clinic, histologic and therapeutic parameters) were assessed using univariate and then multivariate analysis (semi parametric regression (COX's) model). Only three criteria were very important according to the multivariate analysis: 1) invasion of neighboring organs (p < 0.006) with a relative risk score (RRS) of 4.26; 2) intravascular or intralymphatic tumor embols outside the tumor (p < 0.004; RRS = 2.11); 3) invaded distal nodes (located at the origin of the vessels (p < 0.04; RRS = 1.88). A prognosis index was described according to these results. A repartition of the patients in three prognostic groups according to these 3 criteria was proposed. Future, trials should consider these three different prognostic groups.