Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Complementary feeding: A Global Network cluster randomized controlled trial
BMC Pediatrics, Volume 11, Article 4, Year 2011
Notification
URL copied to clipboard!
Description
Background: Inadequate and inappropriate complementary feeding are major factors contributing to excess morbidity and mortality in young children in low resource settings. Animal source foods in particular are cited as essential to achieve micronutrient requirements. The efficacy of the recommendation for regular meat consumption, however, has not been systematically evaluated.Methods/Design: A cluster randomized efficacy trial was designed to test the hypothesis that 12 months of daily intake of beef added as a complementary food would result in greater linear growth velocity than a micronutrient fortified equi-caloric rice-soy cereal supplement. The study is being conducted in 4 sites of the Global Network for Women's and Children's Health Research located in Guatemala, Pakistan, Democratic Republic of the Congo (DRC) and Zambia in communities with toddler stunting rates of at least 20%. Five clusters per country were randomized to each of the food arms, with 30 infants in each cluster. The daily meat or cereal supplement was delivered to the home by community coordinators, starting when the infants were 6 months of age and continuing through 18 months. All participating mothers received nutrition education messages to enhance complementary feeding practices delivered by study coordinators and through posters at the local health center. Outcome measures, obtained at 6, 9, 12, and 18 months by a separate assessment team, included anthropometry; dietary variety and diversity scores; biomarkers of iron, zinc and Vitamin B12 status (18 months); neurocognitive development (12 and 18 months); and incidence of infectious morbidity throughout the trial. The trial was supervised by a trial steering committee, and an independent data monitoring committee provided oversight for the safety and conduct of the trial.Discussion: Findings from this trial will test the efficacy of daily intake of meat commencing at age 6 months and, if beneficial, will provide a strong rationale for global efforts to enhance local supplies of meat as a complementary food for young children.Trial registration: NCT01084109. © 2011 Krebs et al; licensee BioMed Central Ltd.
Authors & Co-Authors
Krebs, Nancy F.
United States, Aurora
University of Colorado Anschutz Medical Campus
Hambidge, K. Michael
United States, Aurora
University of Colorado Anschutz Medical Campus
Mazariegos, Manolo
Guatemala, Guatemala City
San Carlos University
Westcott, Jamie E.
United States, Aurora
University of Colorado Anschutz Medical Campus
Goco, Norman J.
United States, Research Triangle Park
Rti International
Wright, Linda L.
United States, Bethesda
National Institute of Child Health and Human Development Nichd
Koso-Thomas, Marion W.
United States, Bethesda
National Institute of Child Health and Human Development Nichd
Tshefu, Antoinette Kitoto
Congo, Kinshasa
Kinshasa School of Public Health
Bose, Carl Lewis
United States, Chapel Hill
The University of North Carolina at Chapel Hill
Pasha, Omrana
Pakistan, Karachi
The Aga Khan University
Goldenberg, Robert L.
United States, Philadelphia
Drexel University College of Medicine
Chomba, Elwyn Nachanya
Zambia, Lusaka
University Teaching Hospital Lusaka
Carlo, Waldemar A.
United States, Birmingham
The University of Alabama at Birmingham
Kindem, Mark
United States, Research Triangle Park
Rti International
Das, Abhik
United States, Research Triangle Park
Rti International
Hartwell, Ty
United States, Research Triangle Park
Rti International
McClure, Elizabeth M.
United States, Research Triangle Park
Rti International
Statistics
Citations: 41
Authors: 17
Affiliations: 10
Identifiers
Doi:
10.1186/1471-2431-11-4
e-ISSN:
14712431
Research Areas
Food Security
Maternal And Child Health
Mental Health
Study Design
Randomised Control Trial
Cohort Study
Study Approach
Quantitative
Study Locations
Congo
Zambia
Participants Gender
Female