Publication Details

AFRICAN RESEARCH NEXUS

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biochemistry, genetics and molecular biology

Fluorapatite: Efficient catalyst for the Michael addition

Tetrahedron Letters, Volume 44, No. 12, Year 2003

A Michael addition assisted by fluorapatite in heterogeneous media is described. Reaction between mercaptans and chalcone derivatives was studied at room temperature in methanol as solvent. By-products of usual undesirable reactions in Michael addition such as 1,2-addition, bis-addition and polymerisation are not observed. The yields obtained are good to excellent. © 2003 Elsevier Science Ltd. All rights reserved.

Statistics
Citations: 58
Authors: 6
Affiliations: 3
Identifiers
Doi: 10.1016/S0040-4039(03)00323-X
ISSN: 00404039

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