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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt
Liver International, Volume 31, No. SUPPL. 2, Year 2011
Notification
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Description
Background: The hepatitis C pandemic has been systematically studied and characterized in North America and Europe, but this important public health problem has not received equivalent attention in other regions. Aim: The objective of this systematic review was to characterize hepatitis C virus (HCV) epidemiology in selected countries of Asia, Australia and Egypt, i.e. in a geographical area inhabited by over 40% of the global population. Methodology: Data references were identified through indexed journals and non-indexed sources. In this work, 7770 articles were reviewed and 690 were selected based on their relevance. Results: We estimated that 49.3-64.0 million adults in Asia, Australia and Egypt are anti-HCV positive. China alone has more HCV infections than all of Europe or the Americas. While most countries had prevalence rates from 1 to 2% we documented several with relatively high prevalence rates, including Egypt (15%), Pakistan (4.7%) and Taiwan (4.4%). Nosocomial infection, blood transfusion (before screening) and injection drug use were identified as common risk factors in the region. Genotype 1 was common in Australia, China, Taiwan and other countries in North Asia, while genotype 6 was found in Vietnam and other Southeast Asian countries. In India and Pakistan genotype 3 was predominant, while genotype 4 was found in Middle Eastern countries such as Egypt, Saudi Arabia and Syria. Conclusion: We recommend implementation of surveillance systems to guide effective public health policy that may lead to the eventual curtailment of the spread of this pandemic infection. © 2011 John Wiley & Sons A/S.
Authors & Co-Authors
Sievert, William
Unknown Affiliation
Al-Traif, Ibrahim Hamad
Unknown Affiliation
Razavi, Homie A.
Unknown Affiliation
Abdo, Ayman Assad
Unknown Affiliation
Ahmed, Ezzat Ali
Unknown Affiliation
Alomair, Ahmed
Unknown Affiliation
Amarapurkar, Deepak Narayan
Unknown Affiliation
Chen, Chien Hung
Unknown Affiliation
Dou, Xiaoguang
Unknown Affiliation
El-Khayat, Hisham Raafat
Unknown Affiliation
Elshazly, M. A.
Unknown Affiliation
Esmat, Gamal
Unknown Affiliation
Guan, Richard
Unknown Affiliation
Han, Kwanghyub
Unknown Affiliation
Koike, Kazuhiko
Unknown Affiliation
Largen, Angela
Unknown Affiliation
McCAUGHAN, G. W.
Unknown Affiliation
Mogawer, Mohamed S.
Unknown Affiliation
Monis, Ali
Unknown Affiliation
Nawaz, Arif Amir
Unknown Affiliation
Piratvisuth, Teerha
Unknown Affiliation
Sanai, Faisal M.
Unknown Affiliation
Sharara, Ala I.
Unknown Affiliation
Sibbel, Scott
Unknown Affiliation
Sood, Ajit K.
Unknown Affiliation
Suh, Dong Jin
Unknown Affiliation
Wallace, Carolyn M.
Unknown Affiliation
Young, Kendra
Unknown Affiliation
Negro, Francesco
Unknown Affiliation
Statistics
Citations: 543
Authors: 29
Affiliations: 24
Identifiers
Doi:
10.1111/j.1478-3231.2011.02540.x
ISSN:
14783223
e-ISSN:
14783231
Research Areas
Genetics And Genomics
Health System And Policy
Infectious Diseases
Study Design
Cross Sectional Study
Study Approach
Systematic review
Study Locations
Egypt