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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Parkinson's disease in Africa: A systematic review of epidemiologic and genetic studies
Movement Disorders, Volume 21, No. 12, Year 2006
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Description
Parkinson's disease (PD) occurs worldwide, but little is Ewri about PD in Africa. We systematically reviewed publications on PD in Africa, with emphasis on epidemiologic and genetic studies. Articles published between 1944 and December 2004 were identified using several strategies. The studies emanated from 13 African countries (Kenya, Uganda, Tanzania, Ethiopia, Nigeria, Senegal, Ghana, Togo, Libya, Tunisia, Algeria, Zimbabwe, and South Africa). The publications fell into four categories: clinical series (n = 17), prevalence studies (n = 7), incidence studies (n = 1), and genetic studies (n = 3). The clinical series documented the occurrence of PD in Africa and described its clinical characteristics. The prevalence studies suggested some intracontinental geographic variation in PD prevalence. Overall, the prevalence figures and the incidence rates of PD in Africa appeared lower than those reported for European and North American populations. Few genetic studies of PD have been reported from Africa, and none in blacks. There are no case-control or cohort studies of PD reported from Africa. This review provides a summary of PD research in Africa over the past 60 years and highlights the information gaps and potential areas for future research. © 2006 Movement Disorder Society.
Authors & Co-Authors
Okubadejo, Njideka U.
United States, Rochester
Mayo Medical School
Nigeria, Lagos
University of Lagos
Bower, James H.
United States, Rochester
Mayo Medical School
Rocca, Walter A.
United States, Rochester
Mayo Medical School
United States, Rochester
Mayo Clinic
Maraganore, Demetrius M.
United States, Rochester
Mayo Medical School
Statistics
Citations: 106
Authors: 4
Affiliations: 3
Identifiers
Doi:
10.1002/mds.21153
ISSN:
08853185
e-ISSN:
15318257
Research Areas
Genetics And Genomics
Study Design
Cross Sectional Study
Cohort Study
Case-Control Study
Study Approach
Systematic review
Study Locations
Algeria
Ethiopia
Ghana
Kenya
Libya
Nigeria
Senegal
South Africa
Tanzania
Togo
Tunisia
Uganda
Zimbabwe