Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
chemistry
The chiral synthesis of thiazole amino acid enantiomers
Synthetic Communications, Volume 20, No. 15, Year 1990
Notification
URL copied to clipboard!
Description
An efficient modified Hantzsch reaction is described for the synthesis of optically pure thiazole amino acid derivatives from the corresponding amino acids. The method is exemplified by the synthesis of a derivative of L-(Gln)Thz, the novel chiral thiazole amino acid moiety of dolastatin 3, The Cotton effects of thiazole amino acids correlate well with the absolute stereochemistry of these compounds. © 1990, Taylor & Francis Group, LLC. All rights reserved.
Authors & Co-Authors
Bredenkamp, Martin W.
South Africa, Johannesburg
University of Johannesburg
Holzapfel, Cedric Wahl
South Africa, Johannesburg
University of Johannesburg
van Zyl, Wynand J.
South Africa, Johannesburg
University of Johannesburg
Statistics
Citations: 82
Authors: 3
Affiliations: 1
Identifiers
Doi:
10.1080/00397919008053164
ISSN:
00397911
e-ISSN:
15322432