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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Moderate-to-severe anaemia due to afebrile plasmodium falciparum Infection in children aged 6-23 months from the rural district of Kongoussi, Burkina Faso
Journal of Tropical Pediatrics, Volume 54, No. 6, Year 2008
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Description
A population-based cross-sectional study was conducted to investigate the association of haemoglobin concentration and moderate-to-severe anaemia with afebrile Plasmodium falciparum (PF) infection in 456 rural children aged 6-23 months. Capillary blood was obtained for haemoglobin concentration measurement by HemoCue® and malaria detection by blood smear microscopy. Anaemia was noted in 444 (97.4%) children with 194 (42.5%) being moderate-to-severe anaemia. PF infection was noted in 240 (52.6%) children with 117 (25.6%) being afebrile and 123 (27.0%) being febrile. Children with afebrile and those with febrile PF infection were more likely to have moderate-to-severe anaemia than children who were PF -free, with odds ratio (95% confidence interval) of 1.86 (1.07-3.23), p < 0.028 and 2.40 (1.29-4.48), p < 0.001, respectively. These results underline the high burden of both anaemia and PF infection in this population. Strategies aiming at controlling malarial anaemia and based on malaria case-treatment should consider both febrile and afebrile PF infection to allow for a better impact. © The Author [2008]. Published by Oxford University Press. All rights reserved.
Authors & Co-Authors
Ouèdraogo, Hermann Z.
Burkina Faso, Ouagadougou
Institut de Recherche en Sciences de la Santé
Zéba, Augustin Nawidimbasba
Burkina Faso, Ouagadougou
Institut de Recherche en Sciences de la Santé
Dramaix, Michèle Wilmet
Belgium, Brussels
Université Libre de Bruxelles
Donnen, Philippe
Belgium, Brussels
Université Libre de Bruxelles
Statistics
Citations: 18
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.1093/tropej/fmn049
ISSN:
01426338
e-ISSN:
14653664
Research Areas
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Case-Control Study
Study Approach
Quantitative
Study Locations
Burkina Faso