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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Epidemiology of bovine trypanosomiasis in the Ghibe valley, southwest Ethiopia. 2. Factors associated with variations in trypanosome prevalence, incidence of new infections and prevalence of recurrent infections
Acta Tropica, Volume 53, No. 2, Year 1993
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Description
An average of 840 East African Zebu cattle from nine herds in the Ghibe valley, southwest Ethiopia were monitored from January 1986 to April 1990. Each month blood samples were collected for analysis of packed red cell volume (PCV) and detection of trypanosomes. Animals found to be parasitaemic and with a PCV less than 26% were treated with diminazene aceturate at a dose of 3.5 mg/kg body weight. The majority of infections were associated with Trypanosoma congolense (84% of infections in adult cattle and 71% in cattle less than 24 months of age), and the mean percentage of adult animals detected parasitaemic 1 month after treatment of an infection with T. congolense was 27%. In order to assess possible existence of drug resistance, a model was applied which allowed monthly incidences of new infections to be distinguished from recurrent infections. This model showed that the monthly incidence of new infections of T. congolense in adult cattle increased significantly from 11% in 1986 to 24% in 1989 following a concomitant increase in the tsetse challenge. The corresponding increase in overall prevalence of T. congolense was from 17% to 38% and the mean prevalence of recurrent infections increased significantly from 6% to 14%. These findings ruled out the possibility that the high prevalence of trypanosome infections in cattle was due only to a high tsetse challenge and pointed to the existence of T. congolense populations which expressed resistance to diminazene. There were variations associated with season, herd, age and sex in the incidence of new infections, prevalence of recurrent infections and relapse to treatment. © 1993.
Authors & Co-Authors
Rowlands, G. John
Kenya, Nairobi
International Livestock Research Institute Nairobi
Mulatu, Woudyalew
Ethiopia, Addis Ababa
International Livestock Centre for Africa Ilca Addis Ababa
Authiè, Édith
Kenya, Nairobi
International Laboratory for Research on Animal Diseases, Kenya
D'Ieteren, G. D.M.
Kenya, Nairobi
International Livestock Research Institute Nairobi
Leak, Stephen G.A.
Kenya, Nairobi
International Laboratory for Research on Animal Diseases, Kenya
Nagda, S. M.
Kenya, Nairobi
International Livestock Research Institute Nairobi
Peregrine, Andrew S.
Kenya, Nairobi
International Laboratory for Research on Animal Diseases, Kenya
Statistics
Citations: 105
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1016/0001-706X(93)90025-7
ISSN:
0001706X
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Ethiopia