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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
High complexity of Plasmodium vivax infections in symptomatic patients from a rural community in central Vietnam detected by microsatellite genotyping
American Journal of Tropical Medicine and Hygiene, Volume 82, No. 2, Year 2010
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Description
Fourteen published and three newly identified polymorphic microsatellites were used to genotype 69 Plasmodium vivax samples obtained from 39 patients detected over a period of two years who lived in a rural community of central Vietnam. All samples were polyclonal with an average expected heterozygosity of 0.86. Among the 39 patients, 16 experienced 1-5 recurrent episodes of P. vivax malaria, most of them (83%) with a different genotype profile compared with previous infections. The minimal set of microsatellites required for differentiating the genotype profiles of the recurrent infections compared with the full set of 17 microsatellites was explored. A combination of five markers was sufficient to identify all recurrent infections with an unrelated or different genotype profile compared with all previous episodes. Copyright © 2010 by The American Society of Tropical Medicine and Hygiene.
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC2813161/bin/SD3.pdf
Authors & Co-Authors
van den Eede, Peter
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Erhart, Annette
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
van der Auwera, Gert
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
van Overmeir, Chantal
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Thang, Ngo Duc
Viet Nam, Hanoi
National Institute of Malariology, Parasitology and Entomology Hanoi
Hung, Lexuan
Viet Nam, Hanoi
National Institute of Malariology, Parasitology and Entomology Hanoi
Anné, Jozef
Belgium, Leuven
Ku Leuven
D'Alessandro, Umberto
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Statistics
Citations: 50
Authors: 8
Affiliations: 3
Identifiers
Doi:
10.4269/ajtmh.2010.09-0458
ISSN:
00029637
Research Areas
Genetics And Genomics
Health System And Policy
Infectious Diseases