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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Interest of thyroglobulinemia measurement in patients with goiter living in iodine deficiency areas in Benin
Medecine Nucleaire, Volume 35, No. 10, Year 2011
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Description
In the present study, we analyze the results of thyroid hormones and thyroglobulinemia of 162 patients with goiter living in the departments of Collines and Donga, known to be areas of iodine deficiency in Benin. These results are compared with those of 85 healthy subjects living in the same departments. This study is a cross-sectional analytical study carried out from 1st July 2009 to 30th June 2010. The population of patients consisted of seven males and 155 females. The average age was of 45.7 years. Most of the patients were suffering of simple goiter. Only six of them had thyroid nodules. The diagnosis of biological hyperthyroidism was positive for 20 patients; 16 of them had subclinical hypothyroidism and four clinical hyperthyroidism. One case of clinical hypothyroidism was found. All other 141 patients were biologically normal (euthyroidism). Seventeen of the patients (including six patients presenting a thyroid nodule) had a normal thyroglobulin rate. Hyperthyroglobulinemia was observed in all other 145 patients. These results suggest that patients with goiter in zone of iodine deficiency are biologically euthyroid with hyper-thyroglobulinemia. Thyroglobulin dosage is then recommended, especially when nodules are perceptible. © 2011 Elsevier Masson SAS.
Authors & Co-Authors
Amoussou-Guénou, Kuassi M.
Benin, Cotonou
University of Abomey-calavi
Awèdé, Bonaventure L.
Benin, Cotonou
University of Abomey-calavi
Koukpemedji, Louis
Benin, Cotonou
University of Abomey-calavi
Adehan, S. A.
Benin, Cotonou
University of Abomey-calavi
Adjibodé, Omer
Benin, Parakou
Université de Parakou
Gangnabakpo, C. I.
Benin, Cotonou
University of Abomey-calavi
Statistics
Citations: 6
Authors: 6
Affiliations: 2
Identifiers
Doi:
10.1016/j.mednuc.2011.07.003
ISSN:
09281258
Study Design
Cross Sectional Study
Study Locations
Benin
Participants Gender
Female