Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Wind direction and proximity to larval sites determines malaria risk in Kilifi District in Kenya
Nature Communications, Volume 3, Article 674, Year 2012
Notification
URL copied to clipboard!
Description
Studies of the fine-scale spatial epidemiology of malaria consistently identify malaria hotspots, comprising clusters of homesteads at high transmission intensity. These hotspots sustain transmission, and may be targeted by malaria-control programmes. Here we describe the spatial relationship between the location of Anopheles larval sites and human malaria infection in a cohort study of 642 children, aged 1-10-years-old. Our data suggest that proximity to larval sites predict human malaria infection, when homesteads are upwind of larval sites, but not when homesteads are downwind of larval sites. We conclude that following oviposition, female Anophelines fly upwind in search for human hosts and, thus, malaria transmission may be disrupted by targeting vector larval sites in close proximity, and downwind to malaria hotspots. © 2012 Macmillan Publishers Limited. All rights reserved.
Authors & Co-Authors
Midega, Janet T.
Kenya, Kilifi
Centre for Geographic Medicine Research
United Kingdom, London
Imperial College London
Smith, David L.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
United States, Bethesda
National Institutes of Health Nih
Olotu, Ally Ibrahim
Kenya, Kilifi
Centre for Geographic Medicine Research
Mwangangi, Joseph M.
Kenya, Kilifi
Centre for Geographic Medicine Research
Nzovu, Joseph G.
Kenya, Kilifi
Centre for Geographic Medicine Research
Wambua, Juliana K.
Kenya, Kilifi
Centre for Geographic Medicine Research
Nyangweso, George M.
Kenya, Kilifi
Centre for Geographic Medicine Research
Mbogo, Charles Mwaniki
Kenya, Kilifi
Centre for Geographic Medicine Research
Christophides, George K.
United Kingdom, London
Imperial College London
Marsh, Kevin
Kenya, Kilifi
Centre for Geographic Medicine Research
United Kingdom, Oxford
University of Oxford
Bejon, Philip A.
Kenya, Kilifi
Centre for Geographic Medicine Research
United Kingdom, Oxford
University of Oxford
Statistics
Citations: 90
Authors: 11
Affiliations: 5
Identifiers
Doi:
10.1038/ncomms1672
e-ISSN:
20411723
Research Areas
Infectious Diseases
Maternal And Child Health
Study Design
Cohort Study
Study Approach
Quantitative
Study Locations
Kenya
Participants Gender
Female